Eplerenone good for heart failure


No surprises here – the eplerenone trial in heart failure, EMPHASIS-HF, has been stopped early because of the benefit of eplerenone over placebo in heart failure. The study, run by Pfizer, looked at over 3,000 patients with mild heart failure (NYHA II).
EPHESUS has already shown us that eplerenone is useful for hypertension and for congestive heart failure post MI – perhaps these results will extend its usefulness to mild heart failure. 


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