Previously, thrombolysis in stroke has been required within the first three hours, but a few studies (ECASS III and SITS-ISTR being the crowd favourites) from late 2008 showed that lengthening this window was safe.
A recent review of the SITS registry (Safe Implementation of Treatments in Stroke) shows that more and more clinicians are adopting this practice, without sacrificing the number of patients that are being treated in the earlier time window.
Read the abstract from the European Stroke Conference here.
What about you – has your clinical practice changed to broaden the window? Sound off in the comments below.