You might have seen word of this PLCO (Prostate, Lung, Colorectal, Ovarian) trial around the traps; it’s one of the seminal oncology trials of the last decade, and it’s putting out a collection of papers. This one from JAMA looks at the benefit of screening people annually with chest-X rays versus standard of care.
It’s not a small trial; over 77,000 patients in each arm of the trial. About 4 out of 5 adhered to the annual X-ray program (only 1 of 10 patients were advised to have an annual X-ray) , and followed up for over 10 years. There were similar rates of lung cancer in each group, and importantly, the relative risk of mortality was 0.94 with a non significant confidence interval.
So there you go – have a chest X-ray every year won’t drop your risk of dying from lung cancer. The NEJM has already looked at using CT as a screening tool, but that doesn’t come without risk.
Check out the article in JAMA.
source | JAMA
image | NIH